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课程大纲与具体时间安排.doc

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课程大纲与具体时间安排.doc

Lectures on Molecular Evaluation and Scientific Writing by Prof. David M. Irwin June 6-8, 2016 Room 1-24, Laboratory of Southwest Diversity Agenda Monday, June 6 Lecture 1: Introduction to Molecular Evolution (9:00-12:00) Lecture 2: Evolution of Duplicate Genes (2:30-5:30) Tuesday, June 7 Lecture 3: Genome Evolution - 1(9:00-12:00) Lecture 4: Scientific writing (2:30-5:30) Wednesday, June 8 Lecture 5: Genome Evolution – 2 (9:00-12:00) Detailed Outline for Each Lecture Lecture 1 (Monday June 6, morning) Introduction to Molecular Evolution Evolution of Life and the field of molecular evolution Different types of mutations Why is phylogeny important in biology Population thinking Gene duplication and gene families Lecture 2 (Monday June 6, afternoon) Evolution of Duplicate Genes Dating the age of gene duplications Possible fates of gene duplicates Why are duplicate genes maintained in a genome? Pseudogenes Pseudogenes and the origin of new genes Duplicate genes and phylogeny Concerted and mosaic evolution Adaptive evolution Lecture 3 (Tuesday June 7, morning) Genome Evolution - 1 C-value paradox (variation in genome size) Types and roles of Repetitive DNA Genome duplication Lecture 4 (Tuesday June 7, afternoon) Scientific writing Preparing manuscripts Journal selection Abstracts Tables and figure legends Common mistakes Examples How to identify common problems Writing “Response to reviews” Lecture 5 (Wednesday June 8, morning) Genome Evolution – 2 Origin of introns Exon shuffling Role of alternative splicing Epigenetics and evolution Micro RNA and evolution Minimal genomes Ancient DNA

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