金属有机化学国家重点实验室2008年年度进展报告.doc
金属有机化学国家重点实验室2008年年度进展报告.doc
金属有机化学国家重点实验室 学科带头人现状与需求 现有人员 目前学科方向 陆熙炎院士 戴立信院士 麻生明院士 侯雪龙研究员 唐勇研究员 丁奎玲研究员 施敏研究员 刘元红研究员 陈耀峰研究员 游书力研究员 刘国生研究员 李玉学副研究员 段伟良副研究员 金属有机，有机合成 不对称催化，有机合成 金属有机，有机合成 不对称催化，有机合成 金属有机，高分子化学 金属有机，有机合成 金属有机，有机合成 金属络合物化学 稀土金属络合物化学 不对称催化，有机合成 金属有机化学 金属有机计算化学 金属有机化学 发展学科方向 需求计划人数 金属催化的小分子活化 金属络合物及反应化学 后过渡金属有机化学 前过渡金属有机化学 稀土金属有机化学 主族元素金属有机化学 金属有机计算化学 1 1 1 1 1 1 1 1 2OO8 年重大记事 一. 完成 2008－2009 年实验室基金项目和 2007-2008 年实验室自主课 题申请 2008－2009 年实验室基金项目共资助了 33 个项目，其中有机所 11 个，外单位 22 个， 资助总额 220.15 万。2007-2008 年实验室自主课题共资助了 4 个项目，资助总额 780 万。 二．中科院创新团队 6 月 14~17 日中国科学院上海有机所“均相催化研究”国际合作伙伴计划团队在 北京召开了团队 2008 年的工作研讨会，会议邀请到了中国科学院高技术与发展局综 合处杨永峰老师和化工处白路娜、唐清老师，国家自然科学基金委化学部杜灿屏老 师参加，院领导介绍了科学院二期创新和三期创新中有关海外合作团队工作的总体 情况以及项目结题的具体要求， 希望团队认真完成结题工作。 团队海外成员：美国 The State University of New Jersey 的张绪穆教授、美国 University of Virginia 的蒲林教授、 美国 The Ohio State University 的王鹏教授、美国 Texas Tech University 的李桂根教 授、香港中文大学的谢作伟教授、香港科技大学的贾国成教授和团队有机所成员： 麻生明、侯雪龙、唐勇、丁奎岭、施敏、刘元红全体共 12 位成员在会上分别作了 20 分钟学术报告，主要交流团队近一年来的工作进展及将来的工作打算。大家一致认 为我们团队现在的合作形式非常好，交叉效果明显，合作成果正在体现，无论是在 基础研究方面还是面向国家需求方面都取得一些较好的进展，我们一定要做好项目 的结题验收工作。并且认真讨论了项目今年年底结束以后继续开展优势互补的合作 研究的各种具体形式，大家愿意共同努力，继续保持合作，以期取得更多更好的结 果。 10 月 11 日，中科院高技术局刘桂菊副局长带领专家评审组对上海有机所创新 团队国际合作伙伴计划“均相催化研究团队”进行结题评估。上海有机所姜标所长、 郏静芳党委书记、丁奎岭副所长等人参加了评估会，姜标所长致欢迎词。刘桂菊副 局长宣布了以浙江大学黄宪院士为评审组组长的专家组成员：复旦大学黄祖恩教授、 2 金国新教授，苏州大学沈琪教授，华东师范大学汤杰教授，南开大学周其林教授， 中国科技大学龚流柱教授，国家自然科学基金委员会化学处陈拥军研究员，中科院 国际合作局曹京华副局长。作为创新研究团队国际合作伙伴计划负责人的上海有机 所麻生明院士向评审组作了团队研究工作总结汇报，团队海外成员张绪穆教授、王 鹏教授和团队国内成员唐勇研究员等人分别作了工作报告。专家评审组肯定了团队 所取得的成绩，同时认为是个优秀的创新研究团队，同时呼吁国家和有关部门对于 团队继续给与支持。 三. 组织召开 The 3rd International Forum on Homogeneous Catalysis and The First China-Spain Bilateral Symposium on Catalysis 在中西双方国家自然科学基金委员会和上海有机所资助下，由西班牙 ICIQ 的 Antonio M. Echavarren 教授和我所麻生明研究员共同组织的 The 3rd International Forum on Homogeneous Catalysis and The First China-Spain Bilateral Symposium on Catalysis 于 2008 年 9 月 23 日~28 日在上海朱家角召开，会议邀请到了 24 名科学家 分别作 30 分钟的学术报告，并安排了 5 分钟的讨论。其中中方代表分别是中国科学 院上海有机化学研究所的陆熙炎、侯雪龙、刘元红和游书力研究员，中国科学院大 连化学物理研究所的周永贵研究员，北京大学的王剑波和施章杰教授，以及南开大 学的周其林教授；西班牙方面代表分别是 Universidad de Santiago de Compostela 的 José Luis Mascareñas 和 Carlos Saá 教授，Universidad de Zaragoza-Consejo Superior de Investigaciones Cientificas 的 Daniel Carmona 教授，Universidad de Oviedo 的 José Gimeno 教 授 ， University Rovira i Virgili 的 Carmen Claver 教 授 ， ICIQ 的 Feliu Maseras 教授、Miquel A. Pericàs 教授、Anton Vidal 教授和 Antonio M. Echavarren 教 授，Universidad de Valencia 的 Gregorio Asensio 教授，Universidat Jaume I 的 Eduardo Peris 教授；还有加拿大 University of Toronto 的 Mark Lautens 教授，美国 University of California 的 F. Dean Toste 教授和 University of Nevada 的 Liming Zhang 教授，日 本 Kyoto University 的 Tamio Hayashi 教授，以及以色列 Tel Aviv University 的 Moshe Kol 教授。 3 四. 实验室承担的科研项目运行正常 我们实验室主持的 973 项目“物质创造与化学转化过程中的若干前沿科学问题 研究”的两个课题“金属参与的化学键断裂和形成研究”和“手性分子的构筑及相 关规律研究”进展顺利。 在以我室学术带头人为主的国家基金委创新研究群体项目“导向有机合成的金 属有机化学”执行六年顺利结题的基础上，今年实验室又以唐勇作为主持人申请到 了新的创新研究群体项目“化学键活化与可控性重组研究” 。国家基金委优秀实验室 重点项目“金属催化的有机合成方法学研究”进展良好，将于 2009 年年初结题。侯 雪龙研究员主持的基金委重点项目 “有机化学反应中的选择性控制”，唐勇研究员 主持的基金委国际合作项目“用于制备结构可控聚烯烃/烯烃共聚物的催化材料” ， 丁奎岭研究员主持的基金委重点项目“手性催化剂负载化中若干新方法研究”和国 际合作交流重大项目“不对称催化反应研究”以及中科院方向性项目“手性诱导、 传递与放大中的科学问题研究”；施敏研究员主持的基金委重点项目“有机合成中 的串联及多组分反应”今年均进展良好。实验室今年还申请到了一项新的 973 项目 “惰性化学键的选择性激化、重组及控制”中的课题四“小分子二氧化碳、一氧化 碳和氧气等的活化” ，将于 2009 年开始执行。 实验室固定人员通过上述项目的研究，共发表 116 篇论文，其中 Chem. Soc. Rev. 1 篇，Acc. Chem. Res. 1 篇，J. Am. Chem. Soc. 5 篇，Angew. Chem. Int. Ed.8 篇， Chem. Eur. J. 9 篇。同时实验室客座人员在实验室基金资助下共发表 108 篇论文， SCI 收录 106 篇，J. Am. Chem. Soc. 6 篇，Angew. Chem. Int. Ed. 3 篇，Chem. Eur. J. 2 篇。 五．对外交流 实验室今年分别接待了美国、日本、德国、法国等国的 19 位科学家来室访问， 并作了 22 个学术报告；也接待了国内多位专家的来室访问，并作了 4 个精彩学术报 告，具体情况见 12-13 页。同时实验室学术带头人纷纷参加国际国内的重要学术会 议，应邀在国际学术会议上作邀请报告 16 次，在双边学术会议上作邀请报告 11 次， 在国内学术会议上作大会报告 2 次，实验室还承办了今年 10 月在南京召开的第十五 4 届全国金属有机化学学术研讨会。 六．实验室学术委员会工作 实验室今年 10 月 19－20 日在南京召开了 2008 年度学术委员会会议， 会上邀请 到了国家自然科学基金委化学部的陈拥军主任和杜灿屏处长以及中科院高技术局化 工处唐清副处长和白路娜老师的参加，他们为实验室的进一步持续发展提了很多宝 贵的意见和建议。同时本届学术会上邀请到中科院大连化学物理研究所的徐杰研究 员和清华大学的李亚栋教授分别作了题为“有机催化剂的设计及其在烃类氧化中的 应 用 ” 和 “ Promising catalyst:From Monodisperse Nanocrystals to Integrated 3-D Colloidal Spheres and Mesoporous Materials”的学术报告。会议就实验室今后的人才 引进、课题组队伍梯队建设、研究方向和客座课题资助力度等方面展开了热烈讨论。 七．获奖情况 陆熙炎研究员 获 2008 年中国化学会黄耀曾金属有机化学终身成就奖 戴立信，陆熙炎研究员 获 2008 年度中国科学院研究生院杰出贡献教师奖 麻生明研究员 获 2008 年第三届中国化学会黄耀曾金属有机化学奖 麻生明研究员 获 2008 年度中国科学院优秀研究生指导教师 丁奎岭研究员 获 2008 年度中国科学院宝洁优秀导师奖 姜雪峰、叶龙武博士 获 2008 年度中国科学院院长优秀奖 顾振华博士 获 2008 年度中国科学院优秀博士学位论文 康强博士 获 2008 年刘永龄奖学金特别奖 叶龙武 姜雪峰博士 获 2008 年中国科学院研究生院三好学生标兵称号 陆建梅、程鑫、陈刚、郭胜海、王庆刚、郑素清、武文琼、刘震、贺虎、阴国印 10 位同学获 2008 年中国科学院研究生院三好学生称号 姜雪峰博士 获 2008 年中国科学院研究生院优秀学生干部称号 5 金属有机化学国家重点实验室 第二届学术委员会第四次会议简报 金属有机化学国家重点实验室第二届学术委员会第四次会议于今年 10 月 19－ 20 日在南京召开，十八位学术委员中有十四位出席会议，国家自然科学基金委化学 部的陈拥军主任和杜灿屏处长以及中科院高技术局化工处唐清副处长和白路娜老师 与会指导。会议由实验室学术委员会主任席振峰教授主持。这次会议的议程是 1) 室主任作实验室年度工作报告，2) 专家学术报告和交流，3) 部分课题组工作进展 情况汇报，4) 国际学术会议介绍，5)实验室今后工作讨论。 一.实验室常务副主任唐勇研究员汇报了实验室一年来的工作 唐勇常务副主任首先欢迎并感谢各位领导和专家的到会，并感谢大家在过去一 年中对我们实验室工作的大力指导和支持。然后他汇报了实验室一年来的工作，主 要包括研究进展，研究成果，实验室建设和人才培养，基金项目，学术活动和存在 问题等六个方面的工作。 二．专家学术报告和交流 会上由中科院大连化学物理研究所的徐杰研究员和清华大学的李亚栋教授分别 作了“有机催化剂的设计及其在烃类氧化中的应用”和“Promising catalyst:From Monodisperse Nanocrystals to Integrated 3-D Colloidal Spheres and Mesoporous Materials”两个精彩的学术报告，与会代表对每一个报告都进行了充分的讨论和交 流。 三. 课题组工作进展汇报和讨论 这次会上共有五个课题组进行科研工作进展汇报，分别由上海有机所侯雪龙研 究员(不对称催化中的选择性控制)、上海有机所刘国生研究员(金属钯催化的氧化胺 化反应的研究)、安徽煤炭师范学院王磊教授(Development of Supported Catalysts for Practical Carbon-Carbon Bond Formation Reactions: From “Physical Adsorption” to “Chemical Bonding” From “Heterogenous” to “Homogenous”)、武汉大学雷爱文教授 6 (过渡金属催化的成键反应机理研究及其新的应用)和北京大学医学部焦宁教授(生物 活性小分子导向的串联催化反应研究)到会汇报交流工作。委员们和与会代表认真听 取了他们的进展情况和今后工作设想，并就研究工作中的问题提出了中肯的意见和 建议，进行了广泛的学术交流。 四．国际学术会议介绍和讨论 本次会上共介绍了三个国际会议的情况： 1、 北京大学的席振峰教授介绍了今年 6 月在法国召开的国际金属有机化学会议的情 况。 2、上海有机所的游书力研究员介绍今年 7 月在上海召开的华人有机化学会议的情 况，重点介绍了大会报告的内容。 3、 上海有机所的刘元红研究员介绍今年 9 月在上海召开的第三届均相催化论坛暨第 一届中西双边会议的情况，大致介绍了每个报告的情况。 通过这些介绍和讨论，使到会代表及时了解国际上金属有机化学研究的热点和 学科前沿，对拓宽工作思路起到了一定的作用。 五．今后工作讨论 会上代表们就实验室今后的进一步发展展开了热烈讨论。大家一致认为现在实 验室的体量相对其它实验室还比较小，因此一定要重视优秀人才的引进工作，主要 在“传统的金属有机化学、导向聚合的金属有机化学和导向惰性化学键活化的金属 有机化学”这三个方向上引进人才，进一步加强金属室的研究工作。同时代表们看 到，近年来金属室的研究工作进展的比以往要深入，但是还需要在机理的研究上进 一步的加强，认识到只有在研究深入的基础上，才能有更新的研究出来，除了金属 室现有研究人员应在这方面加强外，还应从人才引进上方面来考虑这个问题。另外 代表们也就实验室课题组的规模尤其是队伍的梯队建设和研究方向上注重基础和应 用两方面共同发展等方面进行了讨论。 7 2008～2009 实验室基金课题一览表 序 号 姓 名 2008-01 陆熙炎 上海有机所 阳离子钯催化的芳基对碳-杂原子重键的加成反应 2008-02 麻生明 上海有机所 联烯的锂化反应及其金属参与的偶联反应研究 2008-03 侯雪龙 上海有机所 手性环钯催化的动力学拆分 2008-04 施 基于联萘胺的手性氮杂环卡宾配体的合成及其在 敏 单 位 上海有机所 题 目 不对称催化反应中的应用 2008-05 丁奎岭 上海有机所 新型手性螺环配体的设计合成及其在不对称催化 反应中的应用研究 2008-06 唐 勇 上海有机所 新型单中心聚烯烃催化剂的设计、合成及应用 2008-07 刘元红 上海有机所 金催化的新型有机反应研究 2008-08 陈耀峰 上海有机所 单茚基烯土烷基配合物的合成及其催化的烯烃聚合 (钱长涛) 2008-09 游书力 上海有机所 惰性碳氢键活化及选择性转化研究 2008-10 刘国生 上海有机所 金属催化烯丙位碳氢键活化反应的研究 2008-11 李玉学 上海有机所 Au(I)催化机理的理论研究 2008-12 黄 宪 利用过渡金属催化调控和优化亚甲基环丙烷及其 浙江大学 衍生物的反应选择性 2008-13 沈 琪 苏州大学 2008-14 席振峰 北京大学 锂代硅杂环戊二烯的合成与应用 2008-15 吴 金属与有机小分子共催化合成几类含氮杂环化合物 2008-16 周锡庚 复旦大学 Lewis 酸促进的烯(炔 )丙醇脱氧和亲核取代反应 2008-17 王佰全 南开大学 过渡金属促进的 C-H 活化及相关反应研究 2008-18 王绍武 安徽师范大学 稀土金属化合物引发的芳香醛新型歧化反应研究 2008-19 甘良兵 北京大学 杂环富勒烯反应性能研究 2008-20 朱成建 南京大学 手性双/多核金属配合物合成及其催化不对称反应研究 劼 复旦大学 稀土有机化合物促成的碳氮键形成反应的研究 8 2008-21 陈忠宁 福建物构所 金属有机光电信息功能材料 2008-22 王 磊 淮北煤炭 过渡金属在多功能化离子液中催化的有机合成反应 师范学院 2008-23 周永贵 大化所 双功能醋酸银催化的不对称反应 2008-24 苏成勇 中山大学 可调发光稀土超分子配合物的设计合成 2008-25 郎建平 苏州大学 含[Tp*MS3]-配体的金属有机簇合物的自组装 2008-26 施章杰 北京大学 过渡金属催化的碳氢键活化 2008-27 张兆国 手性催化剂的设计合成及多官能化反应的不对称催化 交通大学 反应的研究 2008-28 张俊良 华东师大 基于缺电子共扼烯炔的高选择性合成反应研究 2008-29 余正坤 大化所 1-炔基 Fischer 卡宾化合物的多反应性研究 2008-30 曹卫国 胂叶立德在立体选择性合成含氟有机杂环化合物中 上海大学 的应用 2008-31 王剑波 北京大学 金属卡宾经由的催化反应研究 2008-32 雷爱文 金属钯催化的偶联反应中还原消除等基元反应的动力学 武汉大学 研究 2008-33 焦 宁 北京大学 钯催化的烯丙基醋酸酯的 Heck 反应研究 9 2007～2008 实验室自主课题一览表 项目一：过渡金属参与的有机化学反应 负责人：麻生明、刘国生 参加骨干：陆熙炎、麻生明、刘国生、韩秀玲 项目二：不对称催化中的金属有机化学 负责人：侯雪龙 参加骨干：戴立信、侯雪龙、丁奎岭、Sandoval Christian A.、王正 项目三：金属配合物的合成、结构与反应化学 负责人：唐勇、刘元红 参加骨干：唐勇、刘元红、陈耀峰、孙秀丽 项目四：惰性分子（化学键）活化中的金属有机化学 负责人：施敏、游书力 参加骨干：施敏、游书力、段伟良、李玉学 10 2008 年全室专利申请、授权一览表 2008 年申请专利 编 号 1 2 3 4 5 6 7 8 9 10 11 专利名称 噁唑啉膦配体在不对称催化 氢化烯酮类化合物以合成含 有α手性碳的酮类化合物中 的应用 轴手性联萘骨架含膦配体的 环钯催化剂、合成方法及其 应用 手性γ-丁内酯及用手性膦 化合物催化不对称烯丙基烷 基化反应的制备方法 多取代环己烷和咪唑催化的 高选择性的合成多取代环己 烷的方法 一种有效的吡咯胺类衍生物 的合成方法 保密专利 双齿亚磷酸酯配体、合成方 法及其在烯烃不对称催化氢 甲酰化反应中的应用 A class of organic compounds containing heteroatom and its applications in preparing single-site ziegler-natta catalyst A class of organic compounds containing heteroatom and its applications in preparing single-site ziegler-natta catalyst A class of organic compounds containing heteroatom and its applications in preparing single-site ziegler-natta catalyst 单茚基稀土配合物的合成以 及应用 申请日 2008-6-25 专利号 200810039495. 3 发明人 侯雪龙、吕伟 静 侯雪龙、莫东 亮、张廷珂、 戴立信 2008-7-11 200810040497. 4 2008-4-2 200810035493. 7 姜迎庆、施敏 2008-6-6 200810038651. 4 刘旭光、施敏 2008-12-30 唐翔鹰、施敏 2008-12-30 200810039496. 8 施敏，姜迎庆 丁奎岭、赵宝 国、彭新高、 王正 US12/275882 唐勇、杨小红、 刘博、孙秀丽、 马志、高原、 王聪 JP 唐勇、杨小红、 刘博、孙秀丽、 马志、高原、 王聪 EP 唐勇、杨小红、 刘博、孙秀丽、 马志、高原、 王聪 2008-6-25 2008-11-21 2008-11-21 2008-12-22 2008-1-23 11 200810032938. 6 陈耀峰、徐信 12 13 14 15 16 17 18 2-甲氨基(4,7-二氢吲哚）化 合物、合成方法及用途 具有樟脑骨架的氮杂环卡宾 前体盐、合成方法及用途 3-吲哚－1－丙烯类化合物、 合成方法和用途 一种合成 3,3'-联中氮茚类化 合物的方法 2-（2-硝基乙基）-4,7-二氢 吲哚化合物、合成方法及用 途 2008-1-9 2008-1-23 2008-3-5 2008-7-9 200810032428. 9 200810033107 200810034242. 7 200810040388. 2 游书力、盛益 飞、李公强 2008-12-30 一类含氮配体过渡金属络合 2008-6-13 物、合成方法及其用途 一种过渡金属络合物、合成 2008-7-25 方法及其用途 12 游书力、 康强、 郑晓建 游书力、 李毅、 冯桢 游书力、刘文 博 游书力、夏纪 宝 200810038929. 8 200810040995. 9 Christian A.sandoval ， 李跃辉 Christian A.sandoval ， 李跃辉 2008 年授权专利 编 号 专利名称 专利号 双核金属络合物的合成及其催化的二氧化 碳和环氧化合物共聚合和环加成反应 CN100358902C 联萘酚骨架的取代双齿亚邻酰胺配体在烯 2 烃氢甲酰化反应中的应用 CN100430139C 1 3 4 一种具有手性中心的恶唑啉环金属催化剂、 合成及用途 含碳氧醚键有机硅化合物、合成方法及其 应用 CN100378111C 5 乙烯共聚催化剂、合成方法和用途 6 7 8 9 10 11 CN100389117C CN100362028C 含卤素取代基的酮亚胺类过渡金属钛配合 物、合成方法和用途 使用金属盐催化苯酚类及本醚类化合物的 硝化方法 全氟烷磺酸盐催化均三甲苯的绿色硝化方 法 蒙脱土催化合成萘和茚衍生物的环境友好 方法 四氢喹啉类化合物及用路易斯酸催化的合 成方法 手性膦硫脲化合物、合成方法及其应用 13 CN100384893C CN100358859C CN100378067C CN100378044C CN100378078C CN100408587C 发明人 丁奎岭、肖友 利 丁奎岭、赵宝 国 侯雪龙、 苑可、 张廷柯、戴立 信 麻生明、 杨青、 肖丰收 谢光勇、钱长 涛、姜卫华 谢光勇、钱长 涛、姜卫华 施敏、尹万坡 施敏、尹万坡 陆建梅、施敏 施敏、邵黎雄 时永灵、施敏 2008 年金属有机化学国家重点实验室来访人员名单 Prof. Shi Yian 美国 Colorado state University 2008, 1, 8 Prof. Mukund Sibi 美国 North Dakota State University 2008, 3, 3 2008, 3, 4 Frof. M. Gaunt 美国 Cambridge University 2008, 4, 14 2008, 4, 15 陈应春教授 四川大学华西药学院 Prof. Shun-Ichi Murahashi 2008, 4, 29 日本 Okayama University of Science 2008, 5, 15 Prof. Richard C. Larock 美国 Iowa State University 2008, 5, 20 2008, 5, 23 苏吉虎博士 德国马普研究所 2008, 5, 27 龚流柱教授 中国科技大学 2008, 5, 30 Pro. Ben zhong Tang 香港科技大学 2008, 6, 3 Pro. Mikiko Sodeoka 日本 NIKEN 2008, 6, 11 Dr. Jian Zhou 德国 Max-Planck-Institut für Kohlenforschung 2008, 6, 25 Pro. Eugene Y.-X. Chen 美国 Colorado State University 2008, 10, 7 Dr.Mark R. Biscoe 美国 Massachusetts Institute of Technology 2008, 10, 8 Prof. Hidehiro Sakurai 日本 Institute for Molecular Science 2008, 10, 13 Prof. Liming Zhang 美国 University of Nevada 14 2008, 10, 14 Prof. Lutz H. Gade 德国 University Heidelberg 2008, 10, 17 Prof.Chien-Tien Chen 台湾 National Taiwan Normal University 2008, 10, 24 Prof. Akio Yamamoto 日本 Tokyo Institute of Technology 2008, 10, 24 Prof. Hiroaki Sasai 日本 Osaka University 2008, 10, 24 Prof. H. B. Kagan 法国 Universite of Paris-South 2008, 10, 25 Dr. Liang Deng 美国 Harvard University 2008, 10, 28 Prof. Benjamin List 德国 Max-Planck-Institut für Kohlenforschung 2008, 11, 13 Dr. Timothy F. Jamison 美国 Massachusetts Institute of Technology 2008, 12, 17 15 二 00 八年专著目录 专著(章节)题目 作者 专著名称 16 出版社名称 年份 页码 主编姓名 二 00 八年论文目录 课题负责人：陆熙炎 课题编号： 2008-01 课题负责人：麻生明 课题编号： 2008-02 1. Studies on Thermal Reactivity 2-Allyl-3-allenylcyclohex-2-enones Zhenhua Gu and Shengming Ma* Chem. Eur. J. 2008, 14, 2453-2464. of -(1,2-Allenyl)butenolides and 2. Heterocycles Based on the Chemistry of Alkylidenecyclopropanes and (Aza-)Cyclopropenes Shengming Ma Pure & Appl. Chem. 2008, 80, 695-706. 3. Rhodium-Catalyzed Highly Regioselective Hydroformylation-Hydrogenation of 1,2-Allenyl Phosphine Oxides and Phosphonates Hao Guo and Shengming Ma* Adv. Synth. Catal. 2008, 350, 1213-1217. 4. Pd(PPh3)4-Catalyzed Diastereoselective Synthesis of Four-membered trans-1,2-Diazetidines from 2,3-Allenyl Hydrazines and Aryl Halides Xin Cheng and Shengming Ma Angew. Chem. Int. Ed.2008, 47, 4581-4583. 5．Cyclizations of 2-(2’,3’-Allenyl)acetylacetates Catalyzed by Gold(I) and Pd(II) Affording Substituted Cyclopentene and 4,5-Dihydrofuran Derivatives with Distinct Selectivity Xuefeng Jiang, Xiaojing Ma, Zilong Zheng, and Shengming Ma* Chem. Eur. J. 2008, 14, 8572-8578. 6. Studies on Palladium Catalyzed Asymmetric Cyclization of 3,4-Allenylic Hydrazines with Organic Halides Wei Shu, Qing Yang, Shengming Ma,* and Guochen Jia Tetrahedron 2008, 64, 11159-11166. 7. An Efficient Synthesis of 2-Vinylic Cyclic 1,3-Alkadienes via the Cp*Ru(II)-Catalyzed Intermolecular Coupling Reactions of Alkynes and Cyclic Allenes Tao Bai, Peng Xue, Li Zhang, Shengming Ma,* and Guochen Jia* Chem. Commun. 2008, 2929-2931. 17 8. Highly Regioselective Synthesis of 1,1,3-Trisubstituted Allenes via Lithiation of 1-Aryl-3-alkylpropadiene, Subsequent Transmetallation, and Pd-catalyzed Negishi Coupling Reaction Jinbo Zhao, Yu Liu, and Shengming Ma* Org. Lett. 2008, 10, 1521-1523. 9. Intermolecular Sequential [4+2]-Cycloaddition-Aromatization Reaction of Aryl-Substituted Allenes with DMAD Affording Phenanthrene and Naphthalene Derivatives Xuefeng Jiang, Wangqing Kong, Jie Chen, and Shengming Ma* Org. & Biomol. Chem. 2008, 3606-3610. 10. Observation of the Neighboring Group Participation of Phosphine Oxide Functionality in the Highly Regio- and Stereo-selective Iodohydroxylation of 1,2-Allenylic Diphenyl Phosphine Oxides by ESI-MS Using H218O as the Probe Hao Guo, Rong Qian, Yinlong Guo, and Shengming Ma * J. Org. Chem. 2008, 73, 7934-7938. 11. Studies on the Factors Controlling the Stereoselectivity in Electrophilic Iodocyclization of Alkylidenecyclopropyl Ketones Jie Chen, Lianghua Lu, and Shengming Ma* Tetrahedron 2008, 64, 8899-8906. 12. Insertion Reactions of Allenes with Palladium Aryl Complexes [PdI(Ph)(PPh3)]2 and PdI(Ph)(dppe) Tao Bai, Liqin Xue, Peng Xue, Jun Zhu, Herman Ho-Yung Sung, Shengming Ma* Ian Duncan Wiliams, Zhenyang Lin,* and Guochen Jia* Organometallics 2008, 27, 2614-2626. 13. An Efficient Approach to 1,5,7,8,9-Pentahydrocyclopenta[h]-2-benzopyran3-one Derivatives via Palladium-catalyzed Tandem Reaction of 2,7-Alkadiynylic Carbonates with 2,3-Allenoic Acids Xiongdong Lian and Shengming Ma* Angew. Chem. Int. Ed. 2008, 47, 8255-8258. 14. Efficient Synthesis of 3-Chlorometheyl-2(5H)-furanones and 3-Chlorometheyl5,6-dihydropyran-2-ones via the PdCl2-Catalyzed Chlorocyclocarbonylation of 2,3- or 3,4-Allenols Xin Cheng, Xuefeng Jiang, Yihua Yu, and Shengming Ma* J. Org. Chem. 2008, 73, 8960-8961. 15. Recent Advances on Asymmetric Synthesis Metal-Catalyzed Enantioselective Allylation Reaction Zhan Lu and Shengming Ma* 18 via Angew. Chem. Int. Ed. 2008, 46, 258-297. 16. PdCl2/NaI-Catalyzed Homodimeric Coupling-Cyclization Reaction of 2,3-Allenols: An Efficient Synthesis of 4-(1',3'-Dien-2'-yl)-2,5-dihydrofuran Derivatives Youqian Deng, Yihua Yu, and Shengming Ma* J. Org. Chem. 2008, 73, 585-589. 17. An Efficient Approach for Monofluorination via Aqueous Fluorolactonization Reaction of 2,3-Allenoic Acids with Selectfluor Chao Zhou, Zhichao Ma, Zhenhua Gu, Chunling Fu,* and Shengming Ma* J. Org. Chem. 2008, 73, 772-774. 18. Studies on Electrophilic Interaction of 2,3-Allenols with Electrophilic Halogen Reagents: Selective Synthesis of 2,5-Dihydrofurans, 3-Halo-3-alkenals, or 2-Halo-2-alkenyl ketones Jing Li, Chunling Fu, Guofei Chen, Guobi Chai, and Shengming Ma* Adv. Synth. Catal. 2008, 350, 1376-1382. 19. An Efficient Approach for Monofluorination via Highly Regioselective Fluorohydroxylation Reaction of 3-Aryl-1,2-allenes with Selectfluor Chao Zhou, Jing Li, Bo Lü, Chunling Fu,* and Shengming Ma* Org. Lett. 2008, 10, 581-583. 20. Pd(OAc)2-Catalyzed Cyclization of 2,3-Allenoic Acids in the Presence of Terminal ,β-Unsaturated Alkynones – A One-pot Highly Stereoselective Synthesis of 4-(3'-oxo-1'(E)-alkenyl)-2(5H)-furanones Guofei Chen,a Rong Zeng,a Zhenhua Gu,b Chunling Fu,a and Shengming Maa Org. Lett. 2008, 10, 4235-4238. 21. Guo Hao book 课题负责人：侯雪龙 1. 课题编号： 2008-03 Zhang, K.; Peng, Q.; Hou, X.-L.*; Wu, Y.-D. Highly Enantioselective Pd-Catalyzed alkylation of Acyclic Amides Angew. Chem. Int. Ed. 2008, 47, 1741 2. Wen-Qiong Wu, Qian Peng, Da-Xuan Dong, Xue-Long Hou* and Yun-Dong Wu* A Dramatic Switch of Enantioselectivity in Asymmetric Heck Reaction by Benzylic Substituents of Ligands 19 J. Am. Chem. Soc. 2008, 129, 9717 3. Chen, D.-D.; Hou, X.-L.*; Dai, L.-X. Unexpected Transfer of Tosyl-Group of ArCH=NTs Catalyzed by N-Heterocyclic Carbene J. Org. Chem. 2008, 73, 5578 4. Zhang, T.-K.; Mo, D.-L.; Dai, L.-X.; Hou, X.-L.* Asymmetric Ring Opening Reaction of Oxabicyclic Alkenes with Aryl Boric Acids Catalyzed by P-Containing Palladacycle Org. Lett. 2008, 10, 3689 5. 张唐志，陈娣，侯雪龙*，戴立信 手性环芳烷单膦配体在脱氢氨基酸的不对称催化氢化中的应用 高等学校化学学报 2008, 29, 2015 6. Yan, X.-X.; Peng, Q.; Li, Q.; Zhang, K.; Hou, X.-L.*; Wu, Y.-D.* Highly Enantioselective Diastereoselectivity-Switchable Mannich Reaction of Glycine Derivatives with Imines J. Am. Chem. Soc. 2008, 130, 14362 7. Zhang, T.-K.; Mo, D.-L.; Dai, L.-X.; Hou, X.-L.* Highly Efficient Kinetic Resolution of 1-Hydroxy-2-aryl-1, 2-dihydronaphthalenes via Dehydration Reaction Catalyzed by Chiral Palladacycle Org. Lett. 2008, 10, 5337 8. Lu, Wei Jing; Chen, Yun Wei; Hou, Xue Long* Ir-Catalyzed Highly Enantioselective Hydrogenation of C=C bond of α, β-Unsaturated Ketones Angew. Chem. Int. Ed. 2008, 47, 10133 9. Jing Yu Wu, Zhi Bin Luo, Li Xin Dai, Xue Long Hou* Tributylphosphine-Catalyzed Cycloaddition of Aziridines with Carbon Disulfide and Isothiocyanate J. Org. Chem. 2008, 73, 9137 课题负责人：施 敏 课题编号： 2008-04 1. Lewis acid catalyzed ring-opening reactions of methylenecyclopropanes with diphenylphosphine oxide in the presence of sulfur or selenium. Min Shi,* Min Jiang and Le-Ping Liu, Org. Bio. Chem. 2007, 5, 438-440. 2. Reactions of methylenecyclobutanes with silver acetate and iodine. Min Jiang, Le-Ping Liu and Min Shi,* Tetrahedron 2007, 63, 9599-9604. 20 3. Lewis Acid-catalyzed Reactions of Mono-Aryl Methylenecyclopropanes with Diethyl Ketomalonate. Le-Ping Liu and Min Shi,* Tetrahedron 2007, 63, 4535-4542. Group Substituted 4. Montmorillonite K-10 Catalyzed Intramolecular Vinylidenecyclopropanes. Jian-Me Lu and Min Shi,* Tetrahedron 2007, 63, 7545-7549. Rearrangement of 5. Aza-Baylis-Hillman Reaction of Salicyl N-Tosylimines with Methyl Vinyl Ketone, Ethyl Vinyl Ketone or Phenyl Vinyl Ketone. Ming-Juan Qi, Min Shi,* Tetrahedron 2007, 63, 10415-10424. 6. Regioselective Control in the Palladium-Catalyzed Isomerization Methylenecyclopropylcarbinols Using Acetic Acid as a Reagent. Min Shi,* Bao-Yu Wang, and Li-Xiong Shao, Synlett 2007, 909-912. of 7. Au(I)-Catalyzed Intramolecular Reaction of Propargylic/Homopropargylic Alcohol with Oxirane. Lun-Zhi Dai and Min Shi,* Chem. Eur. J. 2008, 14, 7011-7018. 8. A Convenient Three-Component Reaction Leading to the Synthesis of Polysubstituted Cyclohexene Derivatives. Xiao-Yang Guan and Min Shi,* Org. Bio. Chem. 2008, 6, 3616-3620. 9. Chiral Congested Phosphine-Amide Bifunctional Organocatalysts in Asymmetric aza-Morita-Baylis-Hillman Reactions of N-Sulfonated Imines with Methyl Vinyl Ketone and Ethyl Vinyl Ketone. Xiao-Yang Guan, Ying-Qing Jiang, and Min Shi,* Eur. J. Org. Chem. 2008, 2150-2155. 10. Chiral Phosphine-Catalyzed Enantioselective Construction of -Butenolides Through Substitution of Morita-Baylis-Hillman Acetates with 2-Trimethylsilyloxy Furan. Ying-Qing Jiang, Yong-Ling Shi and Min Shi,* J. Am. Chem. Soc. 2008, 130, 7202-7203. 11. Aluminum Chloride-Mediated Acylation of Methylenecyclobutanes. A Facile Synthetic Protocol for the Construction of Substituted Cyclopentenes. Min Jiang and Min Shi,* Org. Lett. 2008, 10, 2239-2242. 12. Lewis Acid Mediated Reactions of 1-Cyclopropyl-2-arylethanone Derivatives with Allenic Ester, Ethyl Acetoacetate, and Methyl Acrylate. Min Shi,* Xiang-Ying Tang, and Yong-Hua Yang, J. Org. Chem. 2008, 73, 5311-5318. 13. An Efficient Method for the Synthesis of Vinylbromohydrin and Vinylbromoalkoxy Derivatives and Cyclocarbonylation of -Allenic Alcohols Catalyzed by Palladium Chloride. 21 Wei Li and Min Shi,* J. Org. Chem. 2008, 73, 6698-6705. 14. Brønsted Acid TfOH-Mediated [3+2] Cycloaddition Diarylvinylidenecyclopropanes with Nitriles. Wei Li and Min Shi,* J. Org. Chem. 2008, 73, 4151-4154. Reactions of 15. Dendritic chiral phosphine Lewis bases catalyzed asymmetric aza-MoritaBaylis-Hillman reaction of N-sulfonated imines with activated olefins. Ying-hao Liu and Min Shi,* Adv. Synth. & Catal. 2008, 350, 122-128. 16. Asymmetric Morita-Baylis-Hillman Reaction of Arylaldehydes 2-Cyclohexen-1-one Catalyzed by Chiral Bis(Thio)urea and DABCO. Min Shia,b* and Xu-Guang Liu,b Org. Lett. 2008, 10, 1043-1046. with 17. Cyclometalated cis-Chelated Bidentate N-Heterocyclic Carbene Palladium Complexes. Synthetic, Structural, and Catalytic Studies. Zhen Liu,a Tao Zhang,b and Min Shi,a,b* Organometallics 2008, 27, 2668-2671. 18. Lewis Acid-Catalyzed Reactions of Vinylidenecyclopropanes with Activated Carbon-Oxygen Double Bond: A Facile Synthetic Protocol for Functionalized Tetrahydrofuran and 3,6-Dihydropyran Derivatives. Jian-Mei Lu and Min Shi,* J. Org. Chem. 2008, 73, 2206-2210. 19. LDA-Mediated Selective Addition Reaction of Vinylidenecyclopropanes with Aldehydes, Ketones and Enones: Facile Synthesis of Vinylcyclopropenes, Allenols and 1,3-Enynes. Jian-Mei Lu and Min Shi,* Org. Lett. 2008, 10, 1943-1946. 20. Vilsmeier-Haack Reaction of 1-Cyclopropyl-2-arylethanones. Xiang-Ying Tang and Min Shi,* J. Org. Chem. 2008, 73, 8317-8320. 21. Palladium(II)-Catalyzed Ring Enlargement of 2-(Arylmethylene)cyclopropylcarbinols: Strong Substituent Electronic Nature on the Reaction Pathway. Guo-Qiang Tian, Zhi-Liang Yuan, Zhi-Bin Zhu, and Min Shi,* Chem. Commun. 2008, 2668-2670. 22. Rearrangement of {[2-(Arylmethylene)cyclopropyl]methyl}(phenyl)sulfanes and Selanes via Radical Pair Process. Guo-Qiang Tian, Jia Li, and Min Shi,* J. Org. Chem. 2008, 73, 673-677. 23. Gold(I)-Catalyzed Intramolecular Rearrangement of Vinylidenecyclopropanes. Min Shi,* Lei Wu and Jian-Mei Lu, J. Org. Chem. 2008, 73, 8344-8347. 24. Lewis Acid-Catalyzed Cascade Reactions of Diarylvinylidenecyclopropanes and 1,1,3-Triarylprop-2-yn-1-ols or Their Methyl Ethers. 22 Min Shi,a,b* and Liang-Feng Yao,a Chem. Eur. J. 2008, 14, 8725-8731. 25. Asymmetric Catalytic aza-Morita-Baylis-Hillman Reaction (aza-MBH): Remarkable Functional Group-Caused Reversal Asymmetric Induction. Min Shi,* Ming-Juan Qi, and Xu-Guang Liu, Chem. Commun. 2008, 6025-6027. A 有机所为第二单位： 26. A Fast Catalytic Asymmetric Aza-Morita-Baylis-Hillman Reaction of N-Sulfonated Imines with Methyl Vinyl Ketone in the Presence of Chiral Bifunctional Phosphine Lewis Bases. Zhi-Yu Lei,a Guang-Ning Ma,b Min Shi,*a,b Eur. J. Org. Chem. 2008, 3817-3820. 27. Bifunctional Chiral Phosphine-Containing Lewis Bases Catalyzed Asymmetric Morita-Baylis-Hillman Reaction of Aldehydes with Activated Alkenes. Zhi-Yu Lei,a Xu-Guang Liu,a Min Shi,a,b* Meixin Zhao,a Tetrahedron : Asymmetry 2008, 19, 2058-2062. 28. Phosphine-Catalyzed Annulation of Ethyl (Arylimino)acetates: Synthesis of Highly Functionalized Oxoimidazolidines. Guang-Ning Ma,a Fei-Jun Wang,a Jun Gao,b Min Shi,a,b* Chem. Commun. 2008, 4998-5000. 29. Axially Chiral BINIM and Ni(II)-Catalyzed Highly Enantioselective 1,3-Dipolar Cycloaddition Reactions of Azomethine Ylides and N-Arylmaleimides. Jing-Wen Shi,a Mei-Xin Zhao,a Zhi-Yu Lei,a Min Shi,a,b* J. Org. Chem. 2008, 73, 305. 30. BINAM and H8-BINAM Based Chiral Imines and Zn(OTf)2-Catalyzed Enantioselective Friedel-Crafts Alkylation of Indoles with Nitroalkenes. Zhi-Liang Yuan,a Zhi-Yu Lei,a and Min Shi,a,b* Tetrahedron : Asymmetry, 2008, 19, 1339-1346. 31. Chiral Bidentate Bis(N-Heterocyclic Carbene) Based Palladium Complexes Bearing Carboxylate Ligands: Highly Effective Catalysts for the Enantioselective Conjugate Addition of Arylboronic Acids to Cyclic Enones.** Tao Zhang,a and Min Shi,*a,b Chem. Eur. J. 2008, 14, 3759-3764. 32. N-Heterocyclic Carbene-Acetylamide Palladium Complexes and Their Catalytic Activities in Heck-Mizoroki Reaction. Tao Zhang,a Sijia Liu,a Min Shi,a,b* and Meixin Zhao,a Synthesis 2008, 2819-2824. 33. N-Heterocyclic Carbene Sulfonamide Palladium Complexes and Their Catalytic Activities in Suzuki-Miyaura Coupling Reaction. Tao Zhang,a Wenfeng Wang,a Xingxing Gua and Min Shi,a,b* Organometallics 2008, 27, 753-757. 23 34. Bis(NHC)-Pd(II) Complexes as Highly Efficient Catalysts for Allylation of Aldehydes with Allyltributyltin. Tao Zhanga and Min Shi,a,b* Mei-Xin Zhao, Tetrahedron 2008, 64, 2412-2418. 35. Gold(I) Catalyzed Cycloisomerization of Arylvinylcyclopropenes: An Efficient Synthetic Protocol for the Construction of Indene Skeletons. Zhi-Bin Zhu, and Min Shi,* Chem. Eur. J. 2008, 14, 10219-10222. 课题负责人：丁奎岭 1. 2. 3. 4. 5. 6. 7. 8. 9. 课题编号： 2008-05 Synergistic effect of binary component ligands in chiral catalyst library engineering for enantioselective reactions, Kuiling Ding*, Chem. Commun. 2008, (8), 909-921. Insight into the mechanism of the asymmetric ring-opening aminolysis of 4,4-dimethyl-3,5,8-trioxabicyclo[5.1.0]octane catalyzed by titanium/BINOLate/water system: Evidence for the Ti(BINOLate)(2)-bearing active catalyst entities and the role of water, Hongli Bao, Jing Zhou, Zheng Wang*, Yinlong Guo, Tianpa You, Kuiling Ding*, J. Am. Chem. Soc. 2008, 130, 10116-10127. Chiral Bronsted acid catalyzed asymmetric Baeyer-Villiger reaction of 3-substituted cyclobutanones by using aqueous H2O2, Senmiao Xu, Zheng Wang, Xue Zhang, Xumu Zhang, Kuiling Ding*, Angew. Chem. Int. Ed. 2008, 47, 2840-2843. Modular chiral bidentate phosphonites: Design, synthesis, and application in catalytic asymmetric hydroformylation reactions, Baoguo Zhao, Xingao Peng, Zheng Wang, Chungu Xia*, Kuiling Ding*, Chem. Eur. J. 2008, 14, 7847-7857. Ferrocene-based bidentate phosphonite ligands for rhodium(I)-catalyzed enantioselective hydroformylation, Xingao Peng, Zheng Wang, Chungu Xia*, Kuiling Ding*, Tetrahedron Lett. 2008, 49, 4862-4864. BINOLate - Magnesium catalysts for enantioselective hetero-Diels-Alder reaction of Danishefsky's diene with aldehydes, Haifeng Du, Xue Zhang, Zheng Wang, Hongli Bao, Tianpa You, Kuiling Ding*, Eur. J. Org. Chem. 2008, 2248-2254. Facile Preparation of α-Aryl Nitriles by Direct Cyanation of Alcohols with TMSCN Under the Catalysis of InX3, Gang Chen; Zheng Wang; Jiang Wu; Kuiling Ding*, Org. Lett. 2008, 10, 4573-4576. Christian A. Sandoval*, Yuehui Li, Kuiling Ding, Ryoji Noyori*, The Hydrogenation/Transfer Hydrogenation Network in Asymmetric Reduction of Ketones Catalyzed by [RuCl2(binap)(pica)] Complexes, Chem. Asian J. 2008, 3, 1801-1810. Spiro Skeletons: A Class of Privileged Structure for Chiral Ligand Design, Kuiling Ding*; Zhaobin Han; Zheng Wang, Chem. Asian J. 2008, Early View. DOI: 10.1002/asia.200800192. 课题负责人：唐 勇 课题编号： 2008-06 1. Cu(OTf)2/trisoxazoline catalyzed asymmetric Friedel–Crafts reaction of pyrroles with 24 alkylidene malonates.Chun-Li Cao, You-Yun Zhou, Xiu-Li Sun, Yong Tang* Tetrahedron 2008, 64, 10676–10680. 2. PPh3-catalyzed ylide cyclization for the controllable synthesis of benzobicyclo[4.3.0] compounds: base effects and scope. Long-Wu Ye, Xun Han, Xiu-Li Sun, Yong Tang* Tetrahedron 2008, 64, 1487-1493 3. One-Pot Screening of Titanium Catalysts for Ethylene Polymerization. Xiao-Hong Yang, Xiu-Li Sun, Fu-Bin Han, Bo Liu, Yong Tang*, Zheng Wang, Ming-Li Gao, Zuowei Xie,* and Shi-Zhen Bu Organometallics 2008, 27, 4618–4624. 4. Ethylene homopolymerization and copolymerization withα-olefins catalyzed by titanium complexes bearing [O-NSR] tridentate ligands, Ming-Li Gao, Yue-Feng Gu, CongWang, Xiao-Li Yao, Xiu-Li Sun, Chuan-Feng Li , Chang-Tao Qian, Bo Liu, Zhi Ma, Yong Tang*, Zuowei Xie, Shi-Zheng Bua, Yuan Gao, J. Mol. Cat. A, Chemistry 2008, 292, 62-66 5. Tandem Michael Addition/Ylide Epoxidation for the Synthesis of Highly Functionalized Cyclohexadiene Epoxide Derivatives ， Qing-Gang Wang, Xian-Ming Deng, Ben-Hu Zhu, Long-Wu Ye, Xiu-Li Sun, Chuan-Ying Li, Chun-Yin Zhu, Qi Shen, Yong Tang*, J. Am. Chem. Soc. 2008, 130, 5408-5409. 6. Synthesis of isoxazoline N-oxides and its application in the formal synthesis of dehydroclausenamide Chun-Yin Zhu, Xiu-Li Sun, Xian-Ming Deng, Jun-Cheng Zheng, Yong Tang*, Tetrahedron 2008, 64, 5583–5589. 7. Synthesis and Characterization of Pyrrole-imine [N-NP] Nickel(II) and Palladium(II) Complexes and Their Applications to Norbornene Polymerization Fu-Bin Han, Yu-Liang Zhang, Xiu-Li Sun, Bao-Guo Li, Yang-Hui Guo, Yong Tang* Organometallics, 2008, 27, 1924-1928. 8. Highly Diastereoselective and Enantioselective Formal [4 + 1] Ylide Annulation for the Synthesis of Optically Active Dihydrofurans，Jun-Cheng Zheng, Chun-Yin Zhu, Xiu-Li Sun, Yong Tang*, Li-Xin Dai J. Org. Chem. 2008, 73, 6909–6912. 9. Ylide-Initiated Michael Addition-Cyclization Reactions beyond Cyclopropanes Xiu-Li Sun, Yong Tang* Acc. Chem. Res. 2008, 41, 937. 10. Highly enantioselective synthesis of isoxazoline N-oxides Chun-Yin Zhu, Xian-Ming Deng, Xiu-Li Sun, Jun-Cheng Zheng, Yong Tang* 25 Chem. Commun. 2008, 6,738-740. 11. Tandem Michael addition/ylide olefination reaction for the synthesis of highly functionalized cyclohexadiene derivatives. Long-Wu Ye; Xun Han; Xiu-Li Sun; Yong Tang*, Tetrahedron, 2008, 64, 8149-8154. 12. AsPh3-catalyzed ylide cyclopropanation for the synthesis of trisubstituted vinylcyclopropane derivatives, Hong Jiang, Xiu-Li Sun, Chun-Yin Zhu, Li-Xin Dai, Yong Tang*, Tetrahedron, 2008, 64, 5032-5035 13. Copolymerization of Ethylene with Cycloolefins by Titanium Complexes Containing Tridentate [O-NSR] Ligands, Ming-Li Gao, Xiu-Li Sun, Yue-Feng Gu, Xiao-Li Yao, Chuan-Feng Li, Ji-Ye Bai, Cong Wang, Zhi Ma, Yong Tang*, Zuowei Xie, Shi-Zheng Bu, Chang-Tao Qian, J. Polymer Sci.: Part A: Polymer Chem., 2008, 2807-2819 14. Phosphine-triggered synthesis of functionalized cyclic compounds ， Long-Wu Ye, Jian Zhou, Yong Tang* Chem. Soc. Rev., 2008, 37, 1140–1152 15. Dongmei Liu, Yaorong Wang, Hoi-Shan Chan, Yong Tang, and Zuowei Xie Synthesis, Structure, and Reactivity of Group 4 Metallacarboranes Bearing the Ligand [Me2C(C9H6)(C2B9H10)]3- Organometallics 2008, 27, 5295–5302. (第二单 位). 课题负责人：刘元红 课题编号： 2008-07 1. A Facile Zr-Mediated Multicomponent Approach to Arylated Allylic Alcohols and Its Application to the Synthesis of Highly Substituted Indenes and Spiroindenes. Shenghai Guo and Yuanhong Liu*. Org. Biomol. Chem. 2008, 6, 2064. 2. New Synthetic Approach for the Construction of Multi-Substituted 2-Acyl Furans via IBX-Mediated Cascade Oxidation/Cyclization of cis-2-En-4-yn-1-ols. Xiangwei Du, Haoyi Chen and Yuanhong Liu, Chem. Eur. J. 2008, 14, 9495. 3. Carbon-Carbon Bond Formation of -Alkynylzirconacyclopentenes via Cyclization or Cu/Pd-Mediated Cyclization/Cross-Coupling Sequence with Aryl Iodides. Jingjin Chen, Yuxue Li, Hongjun Gao and Yuanhong Liu. Organometallics, 2008, 27, 5619-5623. 26 4. A General and Efficient Synthesis of Substituted Fluorenes and Heterocycle-Fused Indenes Containing Thiophene or Indole Rings Utilizing a Suzuki-Miyaura Coupling and Acid-Catalyzed Friedel-Crafts Reactions as Key Steps. Guijie Li,a Erjuan Wang,a Haoyi Chen,a Hongfeng Li,a Yuanhong Liu*,a and Peng George Wangb. Tetrahedron 2008, 64, 9033. 5. Dialkyltitanium-mediated titanation of conjugated 1,3-butadiynes and its coupling reactions with aldehydes: a facile synthesis of stereodefined enynes and trans-enynols. Jingjin Chen, Yuanhong Liu*, Tetrahedron Letters 2008, 49, 6655–6658. 6. Brønsted Acid-Catalyzed Highly Efficient Cycloisomerizations of Alkynes Bearing Bis(acetoxy) Groups to Indenyl Ketones. Yuanhong Liu*,a, Shaolin Zhoua, Guijie Lia, Bin Yana, Shenghai Guoa, Yebing Zhoua, Hao Zhang, and Peng George Wang. Adv. Synth. Catal. 2008, 350, 797-801. 课题负责人：陈耀峰 课题编号： 2008-08 1. Reactions of Boratabenzene Yttrium Complexes with KN(SiMe3)2: Salt Elimination and -Ligand Displacement Yuanyuan Yuan, Yaofeng Chen,* G.uangyu Li, and Wei.Xia Organometallics 2008, 27, 6307. 2 ． Divalent Ytterbium Boratabenzene Complex (C5H5BNPh2)2Yb(THF)2: Synthesis, Structure and Solvent-Mediated Redox Transformation Peng Cui, Yaofeng Chen,* Guoping Wang, G.uangyu Li, and Wei Xia Organometallics. 2008, 27, 4013. 3 ． Dialkyl lanthanide Metal Complexes Containing New Tridentate Monoanionic Ligands with Nitrogen Donors Xin Xu, Xiaoyan Xu, Yaofeng Chen,* and Jie Sun Organometallics 2008, 27, 758. 4 ． An Unprecedented Lanthanide Phosphinidene Halide: Synthesis, Structure and Reactivity Peng Cui, Yaofeng Chen,* Xin Xu, and Jie Sun Chem. Commun. 2008, 5547. 5．An ansa-Hetero-Borabenzene Divalent Lanthanide Amide via C-H Bond Cleavage Peng Cui, Yaofeng Chen,* G.uangyu Li, and Wei Xia Angew. Chem., Int. Ed. 2008, 47, 9944. 6 ． Dramatic Electronic Effect of Fluoro Substituents on the Olefin Polymerization Activity of Mono β-Diiminato Titanium Complexes Guangyong Xie, and Changtao Qian* J. Polym. Sci. part A: Polym. Chem., 2008, 46, 211. 27 7 ． A simple, efficient Pd-catalyzed synthesis of N-sulfonylimines from organoboronic acids and tosylbenzimidoyl chlorides Liyan Fan, Feifeng Gao, Weihua Jiang,Minzhi Deng,* and Changtao Qian* Org. Biomol. Chem., 2008, 6, 2133 课题负责人：游书力 1. 2. 3. 4. 5. 6. 7. 课题编号： 2008-09 D-Camphor-derived triazolium salts for catalytic intramolecular crossed aldehyde-ketone benzoin reactions. Li, Yi; Feng, Zhen; You, Shu-Li*. Chem. Commun. 2008, 2263-2265. Highly Enantioselective Friedel-Crafts Reaction of 4,7-Dihydroindoles with Imines by Chiral Phosphoric Acids: Facile Access to 2-Indolyl Methanamine Derivatives. Kang, Qiang; Zheng, Xiao-Jian; You, Shu-Li*. Chem. Eur. J. 2008, 14, 3539-3542. Enantioselective Synthesis of cis-4-Formyl-β-lactams via Chiral N-Heterocyclic Carbene-Catalyzed Kinetic Resolution Li, Gong-Qiang; Li, Yi; Dai, Li-Xin; You, Shu-Li*. Adv. Synth. Catal. 2008, 350, 1258-1262. Ir-Catalyzed Regio- and Enantioselective Friedel-Crafts-Type Allylic Alkylation of Indoles Liu, Wen-Bo; He, Hu; Dai, Li-Xin; You, Shu-Li*. Org. Lett. 2008, 10, 1815-1818. Asymmetric Transfer Hydrogenation of β,γ-Alkynyl α-Imino Esters by a Brønsted Acid. Kang, Qiang; Zhao, Zhuo-An; You, Shu-Li*. Org. Lett. 2008, 10, 2031-2034. Stereoselective Synthesis of γ-Butyrolactones via Organocatalytic Annulations of Enals and Ketoesters Li, Yi; Zhao, Zhuo-An; He, Hu; You, Shu-Li*. Adv. Synth. Catal. 2008, 350, 1885-1890. Highly Enantioselective Friedel-Crafts Reaction of 4,7-Dihydroindoles with β,γ-Unsaturated -Keto Esters by Chiral Brønsted Acids Zeng, Mi; Kang, Qiang; He, Qing-Li; You, Shu-Li*. Adv. Synth. Catal. 2008, 350, 2169-2173. 有机所为第二单位： 8. Organocatalytic Asymmetric Friedel-Crafts Reactions Sheng, Yi-Fei; Zhang, An-Jiang*; Zheng, Xiao-Jian; You, Shu-Li*. Chin. J. Org. Chem. 2008, 28, 605-616. 课题负责人：刘国生 课题编号： 2008-10 [1] Palladium-catalyzed intermolecular aerobic oxidative amination of terminal alkenes: efficient synthesis of linear allylamine derivatives. Liu, G.uosheng;* Yin, Guoyin; Wu, Liang. Angew. Chem. Int. Ed. 2008, 47, 4733-4736 [2] Palladium-catalyzed oxidative cyclization of enyne with hydrogen peroxide as the oxidant. 28 Yin, G.uoyin; Liu, Guosheng.* Angew. Chem. Int. Ed. 2008, 47, 5442-5445 [3] Cobalt-Catalyzed Carbonylative Polymerization of Azetidines Chai, Jianfang; Liu, Guosheng; Chaicharoen, Kittisak; Wesdemiotis, Chrys; Jia, Li.* Macromolecules, 2008, 41, 8980-8985. [4] Palladium-Catalyzed Intramolecular Hydroamination of Allenes Coupled to Aerobic Alcohol Oxidation. Qiu, Shuifa; Wei, Yunyang; Liu, Guosheng.* Chem.-Europ. J. Accepted. 课题负责人：李玉学 课题编号： 2008-11 1. “Carbon-Carbon Bond Formation of -Alkynylzirconacyclopentenes via Cyclization or a Cu/Pd-Mediated Cyclization/Cross-Coupling Sequence with Aryl Iodides” Jingjin Chen, Yuxue Li, Hongjun Gao, and Yuanhong Liu Organometallics 2008, 27, 5619–5623 课题负责人：黄 宪 课题编号： 2008-12 1. Palladium-Catalyzed Highly Regioselective[3 + 2] Cycloaddition Reactions of Alkylidenecyclopropa[b]naphthalenes with Alkenes or Alkynes: An Efficient Synthesis of 1(3)-Alkylidene-2,3-dihydro-1H-benzo [f] indenes and 1-Alkylidene-1Hbenzo[f]indenes, Chen W-L; Cao J; Huang X, Organic Lett., 2008,10（24），5537-5540。 2. A Facile and Efficient Synthesis of Dihydro- isobenzofuran Derivatives via Tandem Pd-catalyzed Coupling, Propargylallenyl Rearrangement, [4 + 2] Cycloaddition and Aromatization Reaction, Shen R-W; Huang X; Chen L-Z, Organic Lett., 2008 ,10(15), 3283-3286. 3. Iodohydroxylation of Alkylidenecyclopropanes. An Efficient Synthesis of Iodocyclo propyl-methanol and 3-Iodo-but-3-en-1-ol Derivatives, Yang Y-W; Huang X, J. Org. Chem., 2008, 72(12), 4702-4704. 4. CAN-Mediated Highly Regioand Stereoselective Oxidation of Vinylidenecyclopropanes: A Novel Method for the Synthesis of Unsymmetrical Divinyl Ketone and Functional Enone Derivatives, Su C-L; Huang X; Liu Q-Y, J. Org. Chem., 2008, 73(16), 6421-6424. 5. Substrate-Controlled Selective Proximal and Distal C-C Bond Cleavage via Lewis Acid Mediated O-Acylation of 2-(Arylmethylene) cyclopropylaldehyde: A Stereoselective Synthesis of Bifunctional Methylenecyclobutanes and 1,3Conjugated Dienes, Miao M-Z; Huang X, J. Org. Chem., 2008, 73(17), 6884-6887. 29 6. Halohydroxylation of 1-Cyclopropylallenes: An Efficient and Stereoselective Method for the Preparation of Multisubstituted Olefins Yu L; Mong B; Huang X, J. Org. Chem., 2008, 73(17), 6895-6898. 7. Huang X; Sha F, A Novel Three-Component Reaction of 2,3-Allenoates, Isocyanides and Carboxylic Acids: Facile Synthesis of Highly N-Substitued Acryl Imide Derivatives, J. Org. Chem., 2008, 73, 1173-1175. 8. Solid-Phase Synthesis of Heterocyclic Nucleoside Analogues: Substituted Uracils Tethered to Isoxazoles, Isoxazolines, and Triazoles from a Selenopolystyrene Resin, Cao J; Huang X, †J. Comb. Chem., 2008, 10(4), 526-533. 9. A Facile Access to Medium- and Large-Size Naphthalena- carbocycles via Lewis Acid Mediated Ring-Expansion Reaction of Bicyclic Vinylidene cyclopropanes, Huang X; Su C-L; Liu Q; Song Y, Synlett, 2008, (2), 299-232. 10. Electrophilic Addition to 1-Cyclopropylallenes: A Highly Efficient and Stereoselective Method for the Preparation of 6- Substituted-1,3-hexadiene, Yu L; Meng B; Huang X, Synlett, 2008, (9), 1331-1334. 11. Intramolecular Cycloisomerization of Aryl-Substituted Alkylidenecyclopropanes via NHC Palladium-Catalyzed Cascade C–C Bond Cleavage/C–H Activation/C–C Bond Formation, Yang Y-W; Huang X, Synlett, 2008, (9), 1366-1370. 12. Titanium(III)-Induced Intramolecular Radical Cyclization of Epoxyallene Ethers: An Efficient Method for Synthesis of Multifunctional Tetrahydrofurans, Xu L-B; Huang X, Tetrahedron Lett., 2008, 49, 500-503. 13. An efficient Stereoselective Synthesis of 1-Iodoor 1-Phenyl selenenyl-2-aryl-3-azabicyclo[3.1.0]hexane via Electrophilic Cyclization of Benzyl-2-arylmethylidenecyclopropylmethyl-amines, Fu W-J; Huang X, Tetrahedron Lett., 2008, 49, 562-565. 14. An Efficient Synthesis of Highly Substituted Furans via the Electrophilic Cyclization of 1-(1-Alkynyl)-cyclopropyl Ketones, Huang X; Fu W-J; Miao M-Z, Tedrahedron Lett., 2008, 49, 2359-2362. 课题负责人：沈 琪 课题编号： 2008-13 1、 Addition of Amines to Nitriles Catalyzed by Ytterbium Amides: An Efficient One-Step Synthesis of Monosubstituted Amidines Junfeng Wang, Fan Xu, Tao Cai, Qi Shen*, Org. Lett. 2008, 10, 445. 2、 Lanthanide Carbene Halides through Protonolysis of Ln-N Bonds by Imidazolium Salts ： Synthesis and Structure of Salicylaldiminato-Functionalized N-Heterocyclic Carbene Lanthanide Bromides Jinguo Zhang, Haisheng Yao, Yong Zhang, Hongmei Sun, and Qi Shen*, Organometallics 2008, 27, 2672. 30 3、 Divalent Lanthanide Complexes: Highly Active Precatalysts for the Addition of N-H and C-H Bonds to Carbodiimides Zhu Du, Wenbo Li, Xuehua Zhu, Fan Xu, and Qi Shen*, J. Org. Chem. 2008, 73, 8966. 课题负责人：席振峰 课题编号： 2008-14 1) Nan Yu, Congyang Wang, Fei Zhao, Wen-Xiong Zhang, and Zhenfeng Xi*, Diversified Reaction Chemistry of 1,4-Dilithio-1,3-dienes with Nitriles: Fine-tuning of Reaction Patterns by Substituents on the Butadienyl Skeleton Leading to Multi-substituted Pyridines and/or 1-pyrrolines Chem. Eur. J. 2008, 14, 5670-5679. 2) Qian Luo,a Chao Wang,a Wen-Xiong Zhang, and Zhenfeng Xi* CuCl-Mediated tandem CO insertion and annulation of 1,4-dilithio-1,3-dienes: formation of multiply substituted cyclopentadienones and/or their head-to-head dimmers Chem. Commun. 2008, 1593-1595. 3) Qifeng Wang, Wen-Xiong Zhang, and Zhenfeng Xi* Pyranylidene Carbene Complexes from 1-Lithio-1,3-Dienes and M(CO)6 (M = Cr, Mo, W): Novel Synthesis and De-metallation reaction Organometallics 2008, 27, 3627-3629. 4) Hui-Jun Zhang, Zhiyi Song, Chao Wang, Christian Bruneau* and Zhenfeng Xi*, Synthesis of stereo-defined 1,1,4,4-tetrahalo- and 1,1,4,4mixed-tetrahalo-1,3-butadienes Tetrahedron Lett. 2008, 49, 624-627. 5) Dongzhen Li, An Shi, Wen-Xiong Zhang, Guangzhen Liu, and Zhenfeng Xi* Selective Synthesis of Multiply Substituted 7-Norbornenone Derivatives or Diels-Alder Cycloadducts from 1,2,3,4-Tetrasubstituted 1,3-Butadienes and Maleic Anhydride with or without Lewis Acids Tetrahedron 2008, 64, 9895-9900. 课题负责人：吴 劼 课题编号： 2008-15 1. Palladium-catalyzed Hiyama cross-couplings of aryl arenesulfonates with arylsilanes Liang Zhang and Jie Wu* J. Am. Chem. Soc. 2008, 130, 12250-12251. 31 2. Palladium-Catalyzed Hiyama cross-coupling reactions of aryl mesylates Liang Zhang, Jiang Qing, Pengyuan Yang, and Jie Wu* Org. Lett. 2008, 10, 4971-4974. 3. Sc(OTf)3-Catalyzed or t-BuOK promoted tandem reaction of 2-(2-(alkynyl)benzylidene) malonate with indole Ke Gao and Jie Wu* Org. Lett. 2008, 10, 2251-2254. 4. Rhodium/N-heterocyclic carbene catalyzed cross-couplings of aryl arenesulfonates with arylboronic acids Liang Zhang and Jie Wu* Adv. Synth. Catal. 2008, 350, 2409-2413. 5. Access to functionalized isoquinoline-N-oxides via sequential cyclization-coupling reactions Qiuping Ding and Jie Wu* Adv. Synth. Catal. 2008, 350, 1850-1854. 6. Tandem addition-cyclization reactions of 2-alkynylbenzenamines with isocyanates catalyzed by PdCl2 Shengqing Ye, Qiuping Ding, Zhiyong Wang, Haibo Zhou, and Jie Wu* Org. Biomol. Chem. 2008, 6, 4406-4412. 7. FeCl3: An efficient catalyst for reactions of electron-rich arenes with imines or aziridines Zhiyong Wang, Xiaoyu Sun, and Jie Wu* Tetrahedron 2008, 64, 5013-5018. 8. Synthesis of 1H-indol-2-yl-(4-aryl)-quinolin-2(1H)-ones via Pd-catalyzed selective cross-coupling reaction and cyclization Zhiyong Wang and Jie Wu* Tetrahedron 2008, 64, 1736-1742. 9. Three-component reaction of 2-alkynylbenzaldehyde, amine, and nucleophile using Lewis acid-surfactant combined catalyst in water Yang Ye, Qiuping Ding, and Jie Wu* Tetrahedron 2008, 64, 1378-1382. 10. Synthesis of 1H-isochromen-1-ylphosphonates via AgOTf-catalyzed reaction of 2-alkynylbenzaldehyde with diethyl phosphite Xingxin Yu, Qiuping Ding, Weizi Wang, and Jie Wu* Tetrahedron Lett. 2008, 49, 4390-4393. 11. AgOTf-Catalyzed one-pot reaction of 2-alkynylbenzaldehyde, amine, and sodium borohydride Qiuping Ding, Xingxin Yu, and Jie Wu* Tetrahedron Lett. 2008, 49, 2752-2755. 课题负责人：周锡庚 课题编号： 2008-16 1. Wen Huang, Pengzhi Zheng, Zhengxing Zhang, Ruiting Liu, Zhenxia Chen, Xigeng Zhou*, “Controllable One-step Synthesis of Spirocycles, Polycycles, Di- and Tetrahydronaphthalenes from Aryl-substituted Propargylic Alcohols”, J. Org. Chem., 2008, 73, 6845. （IF = 3.96, 2 区） 2. Jialiang Wang, Zhenyu Zhu, Wen Huang, Mingli Deng, Xigeng Zhou,* “Air-initiated hydrosilylation of unactivated alkynes and alkenes and dehalogenation of halohydrocarbons by tris(trimethylsilyl)silane under solvent-free conditions”, J. Organomet. Chem. 2008, 693, 2188. （IF = 2.17, 3 区） 3. Xu Xiang, Quansheng Shen, Jialiang Wang, Zhenyu Zhu, Wen Huang, Xigeng Zhou*, “Utility of Dysprosium Diiodide and Metallic Dysprosium as Reductants in Cyclopropanation Reactions of Alkenes with Dichloromethane”, Organometallics, 32 2008, 27, 1959. （IF = 3.83, 2 区） 4. Quansheng Shen, Wen Huang, Jialiang Wang, Xigeng Zhou*, “Ln[N(SiMe3)2]3/RNH2 Catalyzed Mono-addition of Terminal Alkynes to Nitriles: A Novel and Concise Access to Synthesis of Ynones”, Organometallics, 2008, 27, 301. （IF = 3.83, 2 区） 5. Wen Huang, Quansheng Shen, Jialiang Wang, Xigeng Zhou*, “One-step Synthesis of Substituted Dihydro- and Tetrahydroisoquinolines by FeCl3·6H2O Catalyzed Intramolecular Friedel-Crafts Reaction of Benzylamino-Substituted Propargylic Alcohols”, J. Org. Chem., 2008, 73, 1586. （IF = 3.96, 2 区） 6. Ruiting Liu, Pengzhi Zhen, Linhong Weng, Xigeng Zhou,* Chunyuan Liu, “Insertion of Ketenes into Lanthanocene n-Butylamide and Imidazolate Complexes”, J. Organometal. Chem. 2008, 693, 1614. （IF = 2.17, 3 区） 7. Wen Huang, Quansheng Shen, Jialiang Wang, Ruiting Liu, Xigeng Zhou,* ‘Direct substitution of the hydroxy group at the allylic/propargylic position with carbon- and heteroatom-centered nucleophiles catalyzed by Yb(OTf)3”, Chinese J. Chem. 2008, 26, 729-735. （IF = 0.8, 4 区） 课题负责人：王佰全 1. 课题编号： 2008-17 Li, B.; Xu, S.; Song, H.; Wang, B. Reactions of the doubly bridged bis(cyclopentadienyl) dinuclear molybdenum complex (Me2C)(Me2Si)[(5-C5H3)Mo(CO)3]2 with a carboxylate-substituted allene, Eur. J. Inorg. Chem. 2008, 1277-1286. 2. Chen, D.; Xu, S.; Song, H.; Wang, B. Reactions of pyridyl side-chain-functionalized indenes with Ru3(CO)12, Eur. J. Inorg. Chem. 2008, 1854-1864. 3. Li, B.; Xu, S.; Song, H.; Wang, B. Reactions of (Me2C)(Me2Si)[(5-C5H3)Mo(CO)3]2 with phosphinoalkynes: Rearrangement of phosphinoalkynes into phosphido-substituted vinylidenyl ligands by cleavage of P-C(alkyne) bond and formation of P-C(alkene) bond, Eur. J. Inorg. Chem. 2008, 5494-5504. 课题负责人：王绍武 课题编号： 2008-18 1， Yunjun Wu, Shaowu Wang,* Xiancui Zhu, et al, “Synthesis, Characterization, and Catalytic Activity of Rare Earth Metal Amides Supported by Diamido Ligand with a CH2SiMe2 Link” Inorg. Chem. 2008, 47, 5503-5511. 2， Yun Wei , Zeyan Yu , Shaowu Wang*, Shuangliu Zhou, Gaosheng Yang, Lijun Zhang, Guodong Chen, Huimin Qian, Jiaxi Fan, “Synthesis, characterization and catalytic activity of organolanthanide(II) complexes with heterocyclic-functionalized fluorenyl ligands”, J. Organomet. Chem. 2008, 693, 2263-2270. 33 3， Shaowu Wang*, Huimin Qian, Wei Yao, Lijun Zhang, Shuangliu Zhou, Gaosheng Yang, Xiancui Zhu, Jiaxi Fan, Yuyu Liu, Guodong Chen, Hai-bin Song, “Synthesis of rare earth metal complexes incorporating amido and enolate mixed ligands: Characterization and reactivity” Polyhedron, 2008, 27, 2257-2264. 4， Yuyu Liu, Shaowu Wang*, LiJun Zhang, Yunjun Wu, Qihai Li, Gaosheng Yang, Meihua Xie, “Simple Lanthanide Amides [(Me3Si)2N]3Ln(-Cl)Li(THF)3 as Highly Efficient Catalysts for the Nitroaldol Reaction” Chinese J. Chem. 2008, 26, 2267-2272. 5， Yunjun Wu, Shaowu Wang*, Lijun Zhang, Gaosheng Yang, Xiancui Zhu, Chao Liu, Chengwei Yin, Jiewei Rong, “Efficient Guanylation of Aromatic and Heterocyclic Amines Catalyzed by Cyclopentadienyl-Free Rare Earth Metal Amides” Inorg. Chim. Acta 2008, in press. 课题负责人：甘良兵 课题编号： 2008-19 1 Controlled regio- and chemoselective addition of isothiocyanate to the dione moiety of a cage-opened fullerene-mixed peroxide derivative. Xiaobing Yang, Liangbing Gan,* Zheming Wang* Chem. Commun. 2008, 1980-1982. 2 Towards the rational synthesis of norfullerenes. Controlled deletion of one carbon atom from C-60 and preparation of 2,5,9-trioxo-1-nor(C60-Ih)[5,6]fullerene C59(O)3 derivatives. Jiayao Yao, Zuo Xiao, Liangbing Gan,* Dazhi Yang, Zheming Wang* Org. Lett. 2008, 10, 2003-2006. 3 Reactivity of fullerene epoxide: Preparation of fullerene-fused thiirane, tetrahydrothiazolidin-2-one, and 1,3-dioxolane Xiaobing Yang, Shaohua Huang, Zhenshan Jia, Zuo Xiao, Zhongping Jiang, Qianyan Zhang, Liangbing Gan, * Bo Zheng, Gu Yuan, Shiwei Zhang* J. Org. Chem. 2008, 73, 2518-2526. 4 Preparation of fullerenol, fullerenone and aminofullerene derivatives through selective cleavage of fullerene C-H, C-C, C-N and C-O bonds in fullerene-mixed peroxide derivatives Zhongping Jiang, Yan Zhang, Liangbing Gan,* Zheming Wang* Tetrahedron 2008, 64, 11394-11403 5 Preparation of Azafullerene Derivatives from Fullerene-mixed Peroxides and Single Crystal X-Ray Structures of Azafulleroid and Azafullerene Gaihong Zhang, Shaohua Huang, Zuo Xiao, Quan Chen, Liangbing Gan,* Zheming Wang* J. Am. Chem. Soc. 2008 , 130, 12614-12615. 课题负责人：朱成建 课题编号： 2008-20 34 1. “Me3Ga-mediated alkynylation of aldehydes” ， Xuefeng Jia, Hongwei Yang, Ling Fang, Chengjian Zhu, Tetrahedran. Lett., 2008, 49, 1370. 2. “Synthesis of new Schiff base-camphorsulfonyl amide ligands and the in situ screening in the asymmetric additions of organozinc reagents to aldehydes”， Jiangtao Sun, Xu Pan, Zhenya Dai, Chengjian Zhu, Tetrahedron: Asymmetry, 2008, 19, 2451. 课题负责人：陈忠宁 课题编号： 2008-21 课题负责人：王 课题编号： 2008-22 磊 (1) Lei Wang,* Hongji Li and Pinhua Li. Task-specific Ionic Liquid as Base, Ligand and Reaction Medium for the Palladium-catalyzed Heck Reaction. Tetrahedron 2009, 65(1), 364–368. (2) Pinhua Li, Lei Wang,* Min Wang and Feng You. A Novel Gold(I) Iodide Catalyzed Sonogashira Reactions. Eur. J. Org. Chem. 2008, 5946–5951. (3) Min Wang, Pinhua Li and Lei Wang.* Silica Immobilized NHC–CuI: An Efficient and Reusable Catalyst for A3-Coupling (Aldehyde–Alkyne–Amine) under Solventless Reaction Conditions. Eur. J. Org. Chem. 2008, 2255–2261. (4) Pinhua Li, Lei Wang,* Min Wang and Yicheng Zhang. Polymer Immobilized Pyrrolidine-based Chiral Ionic Liquids as Recyclable Organocatalysts for Asymmetric Michael Additions to Nitrostyrenes under Solvent-free Reaction Conditions. Eur. J. Org. Chem. 2008, (22), 1157–1160. (5) Pinhua Li, Lei Wang* and Yicheng Zhang. SiO2–NHC–Cu(I): An Efficient and Reusable Catalyst for [3+2] Cycloaddition of Organic Azides and Terminal Alkynes under Solvent-free Reaction Conditions at Room Temperature. Tetrahedron 2008, 64(48), 10825-10830. (6) Pinhua Li, Lei Wang,* Yicheng Zhang and Guanwu Wang. Silica Gel Supported Pyrrolidine-based Chiral Ionic Liquid as Recyclable Organocatalyst for Asymmetric Michael Addition to Nitrostyrenes. Tetrahedron 2008, 64 (32), 7633–7638. (7) Tao Miao and Lei Wang*. Polystyrene-Iimmobilized Pyrrolidine as a Highly Stereoselective and Recyclable Organocatalyst for Asymmetric Michael Addition of Cyclohexanone to Nitroolefins. Tetrahedron Lett. 2008, 49(13), 2173–2176. (8) Pinhua Li, Lei Wang,* Yicheng Zhang and Min Wang. Highly Efficient Three-component (Aldehyde–Alkyne–Amine) Coupling Reactions Catalyzed by a Reusable PS-supported NHCAg(I) under Solvent-free Reaction Conditions. 35 Tetrahedron Lett. 2008, 49, 6650–6654. (9) Tao Miao, Lei Wang,* Pinhua Li and Jincan Yan. A Highly Efficient and Recyclable Ionic Liquid-Anchored Pyrrolidine Catalyzed Enantioselective Michael Additions. Synthesis 2008, (23), 3828–3834. (10) Hongqiang Liu, Lei Wang* and Pinhua Li. Highly Efficient and Recyclable Palladium Catalyst Anchored on Organic-Inorganic Hybrid Material: Application in the Heck Reaction. Synthesis 2008, (15), 2405–2411. (11) Jincan Yan and Lei Wang.* Merrifield Resin Supported Dipeptides: Efficient and Recyclable Organo- catalysts for Asymmetric Aldol Reactions under Neat Reaction Conditions. Synthesis 2008, (13), 2065–2072. (12) Qiang Wu, and Lei Wang.* Immobilization of Copper(II) in Organic–Inorganic Hybrid Materials: A Highly Efficient and Reusable Catalyst for the Classic Ullmann Reaction. Synthesis 2008, (13), 2007–2012. (13) Tao Miao, and Lei Wang*. Regioselective Synthesis of [1,2,3]-Triazoles Catalyzed by a Silica-supported Copper(I) Catalyst. Synthesis 2008, (3), 363–368. (14) Zuli Wang, Lei Wang* and Pinhua Li. Silica-Anchored Proline-Copper(I) as an Efficient and Recyclable Catalyst for the Sonogashira Reaction. Synthesis 2008, (9), 1367–1372. (15) Liyuan Zhang, Lei Wang,* Hongji Li and Pinhua Li. Application of Highly Efficient, Recyclable Organic–Inorganic Hybrid Material Immobilized Palladium Catalyst in Amine-, and Phosphine-Free Suzuki-Miyaura Reaction. Synth. Commun. 2008, 38(10), 1498–1511. (16) Jincan Yan, Li Zhou and Lei Wang*. Amination Reactions of Aryl Halides with Nitrogen-containing Reagents Catalyzed by CuI in Ionic Liquid. Chin. J. Chem. 2008, 26(1),165–169. (17) Liyuan Zhang and Lei Wang.* Immobilized Palladium on Organic–Inorganic Hybrid Materials: a Novel and Reusable Catalyst for the Copper-Free Sonogashira Coupling Reaction. Chin. J. Chem. 2008, 26, 1601–1606. (18) Min Wang and Lei Wang.* Heterogeneous Palladium Chloride Catalyzed Ligand-free Suzuki–Miyaura Coupling Reactions at Ambient Temperature. Chin. J. Chem. 2008, 26, 1683–1688. (19) Zuli Wang, Lei Wang* and Jincan Yan. Palladium Immobilized on Silica Gel: a Novel and Reusable Catalyst for Heck Reaction. Chin. J. Chem. 2008, 26, 1721–1726. (20) Qiang Wu, and Lei Wang.* Fluoroquinolones as Effective Ligands for Palladium Catalyzed Heck Reactions. Chin. J. Org. Chem. 2008, 28(9), 1655–1659. 36 课题负责人：周永贵 课题编号： 2008-23 1. You-Qing Wang, Chang-Bin Yu, Da-Wei Wang, Xiao-Bing Wang, Yong-Gui Zhou.* Enantioselective Synthesis of Cyclic Sulfamidates via Pd Catalyzed Hydrogenation. Org. Lett. 2008, 10, 2071-2074. 课题负责人：苏成勇 课题编号： 2008-24 1. Assembly of CdI2-Type Coordination Networks from Triangular Ligand and Octahedral Metal Center: Topological Analysis and Potential Framework Porosity, S.-R. Zheng, Q.-Y. Yang, Y.-R. Liu, J.-Y. Zhang, Y.-X. Tong, C.-Y. Zhao, and C.-Y. Su,* Chem. Commun., 2008, 356-358. 2. Guest-inclusion Behaviour of Double-strand 1D Coordination Polymers Based on N,N’-Type Schiff-base Ligands, Q. Wang, R. Yang, C.-F. Zhuang, J.-Y. Zhang,* B.-S. Kang, C.-Y. Su,* Eur. J. Inorg. Chem. 2008, 1702-1711. 3. Assembly of 1D meso coordination polymer from a chiral mononuclear complex by N-deprotonation of the tris(2-benzimidazolyl) ligand, Chun-Long Chen, Qian Zhang, Jun-Hua Yao, Jian-Yong Zhang, Bei-Sheng Kang, Cheng-Yong Su*, Inorg. Chim. Acta. 2008, 361, 2934–2940. 课题负责人：郎建平 课题编号： 2008-25 1. Synthetic and Structural Chemistry of Group 11 and 12 Metal Complexes of the Zwitterionic Ammonium Thiolate Ligands, X. –Y. Tang, H. –X. Li, J. –X. Chen, Z. –G. Ren, J. –P. Lang*, Coord. Chem. Rev., 2008, 252, 2026-2049. 2. Assembly of [(η5-C5Me5)MoS3Cu3]-Supported One-Dimensional Chains with Single, Double, Triple or Quadruple Strands, W. H. Zhang, Y. L. Song, Z. H. Wei, L. L. Li, Y. J. Huang, Y. Zhang, J. –P. Lang*, Inorg. Chem., 2008, 47, 5332-5346. 3. Construction of Symmetric and Asymmetric Mo/S/Cu Clusters from a Cluster Precursor [Et4N]2[(edt)2Mo2S2(μ-S)2] (edt = Ethanedithiolate), Z. –H. Wei, H. –X. Li, W. –H. Zhang, Z. –G. Ren, Y. Zhang, J. –P. Lang*, B. F. Abrahams, Inorg. Chem., 2008, 47, 10461-10468. 课题负责人：施章杰 课题编号： 2008-26 课题负责人：张兆国 课题编号： 2008-27 课题负责人：张俊良 课题编号： 2008-28 课题负责人：余正坤 课题编号： 2008-29 (1) Rhodium-Catalyzed Regioselective C-H Functionalization via Decarbonylation of Acid Chlorides and C-H Bond Activation under Phosphine-Free Conditions. 37 Zhao, X. D.; Yu, Z. K.* J. Am. Chem. Soc. 2008, 130, 8136-8137. (2) A Toluene Guest in a Poly(heteronuclear) Complex Host of Ferrocenyl(CH2)2-Bridged Bispyrazole. Tan, W. Q.; Yu, Z. K.;* He, W.; Wang, L. D.; Sun, J.; Chen, J. Z. Organometallics 2008, 27, 4833-4836. (3) Ruthenium(II) Complexes Bearing a Pyridyl-Supported Pyrazolyl-N-Heterocyclic Carbene (NNC) Ligand and Their Catalytic Activity in Transfer Hydrogenation of Ketones. Zeng, F. L.; Yu, Z. K.* Organometallics 2008, 27, 6025-6028. (4) Efficient Copper(II)-Catalyzed Addition of Activated Methylene Compounds to Alkenes. Li, Y.; Yu, Z. K.;* Wu, S. Z. J. Org. Chem. 2008, 73, 5647-5650. 课题负责人：曹卫国 1. 课题编号： 2008-30 胂叶立德与具有对三氟甲基苯基及双吸电子基团烯烃的反应研究 钱嘉贤 曹卫国 张慧 陈杰 邓红梅 有机化学 27(11).1392-1396(2007) 2. 朱士正 Stereoselective Synthesis of Highly Substituted trans-2,3-Dihydrofuran and trans-1,2Cyclopropane Derivatives Containing Sulfonyl Groups 3. 4. Weiguo Cao, Hui Zhang, Jie Chen, Xiaohong Zhou, Min Shao and Mark C. McMills Tetrahedron 64(1).163-167(2008) Highly Stereoselective Synthesis of Cyclopropyl Heterocycle via Cyclopropanation of Olefin with Arsonium Salt Zhongjiao Ren, Weiguo Cao, Weiqi Tong, Jie Chen and Changqing Wang J. Heterocyclic Chem. 45.85-90(2008) Stereoselective Synthesis of trans-2-Thien--oyl-3-[(un)substituted phenyl]-4-acetyl-5- methyl -2,3-dihydrofurans Haiyan Jiang, Weiguo Cao, Hui Zhang, Jie Chen, Rushu Sun, Hongmei Deng, Min Shao, 5. 6. Shizheng Zhu Chin. J. Chem. 26(4).736-740(2008) Highly Stereoselective Construction of Spiro[Cyclopropane-1,4’-pyrazolin-5’-one] with Alkene and Arsonium Ylide Zhongjiao Ren, Weiguo Cao, Jie Chen, Yali Chen, Hongmei Deng, Min Shao and Danyi Wu Tetrahedron 64(22).5156-5161(2008) A Facile Preparation of trans-1,2-Cyclopropanes Containing p-Trifluoromethylphenyl Group 38 and Its Application to the Construction of Pyrazole and Cyclopropane Ring Fused Pyridazinone Derivatives Weiguo Cao, Hui Zhang, Jie Chen, Hongmei Deng, Min Shao, Lu Lei, Jiaxian Qian and Yuan Zhu Tetrahedron 64(28).6670-6674(2008) 7. Solvent-free One-pot Approach for Synthesis of Substituted 2-Aminochromenes Dong Zhou, Zhongjiao Ren, Weiguo Cao, Jie Chen, Hongmei Deng J. Heterocyclic Chem. 45.1865-1867(2008) 8. Triphenylarsine-Catalyzed Cyclopropanation: Highly trans-2,3-Dihydro-spiro[cyclopropane-1,2’-indan-1’,3’-dione] Stereoselective Synthesis from and Alkene of Phenacyl Bromide Zhongjiao Ren , Weiguo Cao, Weiqi Tong , Jie Chen, Hongmei Deng and Danyi Wu Synth. Commun. 38(13).2200-2214(2008) 9. Ring-Expansion Reaction of Cyclopropane: A Novel Process for Synthesis of Bicyclic Dicarboximides from Cyclopropyldicarboximides and Carbon Nucleophile Zhongjiao Ren, Weiguo Cao, Yeying Lu,Yun Wang and Sihui Wang Synth. Commun. 38(13).2215-2226(2008) 10. Study on the Reaction of Electron-deficient Cyclopropane Derivatives with Aromatic Amines Yali Chen, Weiguo Cao, Meifei Yuan, Huihui Wang, Weiyu Ding and Xiangming Xu Synth. Commun. 38(19).3346-3353(2008) 11. Highly Stereoselective Synthesis of ,γ-Disubstituted and -Trisubstituted Butyrolactones Xiaoyu Wu, Weiguo Cao, Hui Zhang, Jie Chen, Haiyan Jiang, Hongmei Deng, Min Shao, Jiaping Zhang, Huiyun Chen Tetrahedron 64(45).10331-10338(2008) 12. Highly Stereoselective Synthesis of trans-1,2-Cyclopropane Derivative from Semistabilized Arsonium Ylide by Phase-Transfer-Catalysis Reaction Huihui Wang, Yali Chen, Weiguo Cao, Han Ding, Jie Chen, Hongmei Deng, Min Shao Synthesis 2008(24),3995-4001 课题负责人：王剑波 课题编号： 2008-31 1) Sequential Copper(I)-Catalyzed Reaction of Amines with o-Acetylenyl Substituted Cheng Peng, Jiajia Cheng, and Jianbo Wang Advanced Synthesis & Catalysis, 2008, 350, 2359-2364. 2) Palladium-catalyzed cyclopropanation aryldiazocarbonyl compounds Shufeng Chen, Jian Ma, and Jianbo Wang Tetrahedron Letters, 2008, 49, 6781-6783. 课题负责人：雷爱文 of 课题编号： 2008-32 39 electron-deficient olefins with 课题负责人：焦 宁 课题编号： 2008-33 40