附件4：会议论文摘要模板.docx

中国化学会第 12 届全国天然有机化学学术会议论文摘要 Metabolites from endophytic Diaporthe sp. JC-J7 in Dendrobium nobile Lindl Ming Hu, Hai-Yue Yin, Zhuo-Xi Zhang, Qing-Yan Zhou, Ya-Mei Wu, Li-Jiao Shi, Bang-Yan Wang, Ya-Bin Yang *, Zhong-Tao Ding * Functional Molecules Analysis and Biotransformation Key Laboratory of Universities in Yunnan Province, School of Chemical Science and Technology, YunnanUniversity, No. 2, Cuihu North Road , Kunming, China, 650091 *Email:ybyang@ynu.edu.cn; ztding@ynu.edu.cn Abstract Diaporthe sp. are living in a wide range of hosts and have often been regarded as plant pathogens[1]. They are known to cause diseases on a wide range of plant hosts including root and fruit rot[2]. Diaporthe sp. produce a variety of metabolites with different bioactivities[3]. As a part of our project to searching for new bioactive compounds from endophytic fungi of medical plants in the Yunnan province in China. Diaporthe sp. was collected from the stem of Dendrobium nobile Lindl. Six known compounds (1-6) with various structure types were isolated from Diaporthe sp. JCJ7. These compounds were elucidated on the basis of their 1D, 2D NMR spectra and mass spectrometric data. Their structures were determined as dothiorelones A (1)[4], dothiorelones J (2)[5], 8-O-acetylmultiplolide A (3)[6], (4E)-6, 7, 9-trihydroxydec-4-enoicacid (4)[6], multiplolide A (5)[6] and 4-Hydroxybenzeneethano (6)[7]. These compounds were found for the first time in Diaporthe. Keywords: Diaporthe sp.; Metabolites; Structural elucidation. References [1] Gomes, R. R.；Glienke, C.；Videira, S. I. R.；Lombard, L. Persoonia. 2013, 31 (1): 1. [2] Mostert, L.; Crous, P. W.; Kang, J. C.; Phillips, A. J. L. Mycologia. 2001, 93: 146 [3] Chepkirui, C.; Stadler, M. Mycol. Prog. 2017, 16 (5): 477. [4] Thippaya, K.; Xin, X.; Vatchain , R.; Souwalak, P. Phytochem. Lett. 2017, 22: 235. [5] Kornsakulkarn, J.; Somyong, W.; Supothina, S.; Boonyuen, N. Tetrahedron. 2015, 71 (48): 9112. [6] Tan,Q. F.; Yan, X. F.; Lin, X.; Huang,Y. J. Helv Chim Acta. 2010, 90 (9): 1811. [7] Qian, Y. X.; Kang, J. C.; Luo, Y. K.; He, J.; Wang, L. Chem. Nat. Compd. 2017, 53 (4): 1. 中国化学会第 12 届全国天然有机化学学术会议论文摘要 南五味子属植物的化学成分和生物活性研究 普建新，雷春，高雪梅，杨建红，董可，孙汉董* 中国科学院昆明植物研究所植物化学与西部植物资源持续利用国家重点实验室，昆明，650204 *Email:hdsun@mail.kib.ac.cn 五味子科（Schisandraceae）包括五味子属（Schisandra）和南五味子属（Kadsura）两个 属，其中南五味子属全世界共有 25 种，我国有 11 种（包括两个变种） ，主要分布于西南和东 南部地区，其药用部位主要是藤茎，根和果实，具有补血活血、祛风除湿、行气止痛的功效； 常用于风湿、胃痛、痛经、骨痛及急慢性肠胃炎等症，是一类重要的药用植物 1-3。前人的研 究结果表明，该属植物主要成分为木脂素类化合物，另外还有三萜酸及三萜酸内酯类化合物， 具有较强生物活性的成分主要为木脂素类化合物 4-6。 本课题组迄今为止，已对西南地区产的八种南五味子属植物进行了系统的研究，共分离 鉴定了 406 个化合物，其中新化合物 154 个，涉及三萜、降三萜、木脂素、倍半萜、甾体、 黄酮、酚性成分、脂肪酸等各种结构类型，发现了一些新颖结构类型和具有较强生物活性的 化合物。共发表研究论文 14 篇，均为 SCI 收录论文，IF 为 43.739，其中学科前 15％论文 7 篇，占总论文 50％；申请发明专利两项，均已授权。 参考文献： (1) 侯宽昭，中国种子植物科属词典(第二版)，科学出版社，1998，254. (2) 陈道峰，徐国钧，徐珞珊，金蓉鸾，中草药，1993，24，34-37. (3) 李晓光，罗焕敏，中国中药杂志，2003，28，1120-1124. (4) Liu Jia-Sen and Li Liang. Phytochemistry, 1993, 32, 1293-1296. (5) Li Lian-Niang and Xue Hong. Phytochemistry, 1990, 29, 2730-2732. (6) Noriyuki Ookawa, Yukinobu Ikeya, Ko Sugama, Heihachiro Taguchi and Masao Maruno. Phytochemistry, 1995, 39, 1187-1191.