张冬明_年会摘要.doc

Local atomic structure in acupuncture points studied by Fe K-edge EXAFS Abstract Traditional Chinese acupuncture is becoming increasingly popular in western countries but its underlying anatomy and physiology have not been characterized. On the other hand, structural studies are very important for understanding the nature of biological properties in biology system all the time. In this work, Extended X-ray Absorption Fine Structure (EXAFS) of Fe K-edge was used to investigate the Fe local atomic structures of acupuncture points (acupoints) and non-acupoints of human beings. Acupoints samples of Guanyuan, Neiguan and Sanyinjiao were got from anatomical experts of The Second Military Medical University, China. Besides, the EXAFS spectra were collected at BL13B of Photo Factory (PF) of High Energy Accelerator Research Organization, Japan. Apart from the nitrogen neighbors around the central iron atom, oxygen neighbors were also investigated. Not only did we find that the Fe-O mean coordination numbers were obviously different between acupoints and non-acupoints, but also we found that the Fe-O and Fe-N bonds length increased in those samples from acupoints to non-acupoints. With the increase of Fe-N bond length of non-acupionts, the ability of transporting oxygen decreases. As a result of the change of Fe-O coordination number and the Fe-O bond length from acupoints to non-acupoints, there must be a close relationship between the N-Fe-O combinative structure and the difference of obvious structure and function in and out of acupoints.